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Host: Betsy Stovsky RN, MSN Dr. Leslie Cho, Section Head, Preventive Cardiology and Rehabilitation and Director of Women’s Cardiovascular Center discusses tips for health care providers in treating statin intolerance. Although many patients report statin-related muscle symptoms, studies indicate that the majority of these patients can tolerate a statin … myalgia without a significantly raised CK, then a change of statin might allow satisfactory control of lipid levels without a recurrence of intolerance if a patient has muscle related side effects then a water-soluble (hydrophilic) statin … She covers common issues such as symptom management, medication choices, titration of meds, monitoring patients on statins… if mild side effect e.g. Here we present the mechanisms of statin intolerance … Statin intolerance is a commonly encountered clinical problem for which useful management strategies exist. The following are key points to remember from a systematic review for management of patients with dyslipidemia: Although statins are a mainstay of treatment for patients with dyslipidemia who are at risk for cardiovascular disease (CVD), a substantial subset of patients become intolerant to statins … Therefore, in patients who are deemed “statin-intolerant,” lifestyle changes and alternative classes of drugs should be pursued to achieve LDL-C target levels and minimize risk. Lipid Management for Patients with Statin Intolerance Richard Clarens, PharmD UND School of Medicine & Health Sciences Department of Family & Community Medicine Altru Family Medicine Residency OBJECTIVES • Review current guidelines of lipid management for dyslipidemia • Define and identify patients who are statin intolerant.

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